Rindieron su Trabajo Integrador Final en el Centro Universitario San Francisco (CUSF) con la presencia de familiares, amigos y autoridades. 

Aldana Sanchez, Matias Bordese, Augusto Buratto, Darío Ferreyra y Virginia Goitea son los primeros estudiantes de Diseño Industrial en rendir el Trabajo Integrador Final en el Centro Universitario San Francisco (CUSF).

Hace cinco años la Universidad Nacional de Villa María (UNVM) inauguró su extensión en aquella localidad. Seis meses después el Instituto Académico y Pedagógico de Ciencias Básicas y Aplicadas (IAPCByA) incorporó la carrera de Diseño Industrial a la oferta académica.

Estos cinco jóvenes, que apostaron por la educación pública y gratuita, rindieron sus trabajos ante un auditorio repleto de familiares, amigos y también autoridades.  El decano del Instituto, Germán Cassetta los acompañó y felicitó. “Estos primeros egresados significan un importante avance para la ciudad en la que estudiaron, donde también ya están trabajando”.

Los trabajos

Los egresados presentaron dos proyectos y ambos relacionados al trabajo del productor de campo. Todos obtuvieron la calificación 10.

Matías y Darío diseñaron un producto abocado al eje agrícola-ganadero con la temática de engorde de hacienda y dirigido a pequeños productores.

Propusieron “Huella Vacuna”, que consiste en una pista de alimentación modular.  “Permite mejorar el bienestar animal en confinamiento, reduciendo los días de encierro, atendiendo las problemáticas de anegamientos por barro, control de efluentes, estrés animal y enfermedades bovinas”, señaló Darío.

Comentó que es un diseño que incita al productor a aplicar buenas prácticas para actividad de engorde, como las que que ofrece el Instituto Nacional de Tecnología Agropecuaria (INTA).

En tanto que Aldana, Augusto y Virginia desarrollaron “Cowalt”, un sistema para bienestar y descanso también para el ganado bovino.

“Fue diseñado específicamente para resolver la problemática de la mastitis”, dijo Augusto. Explicó que es una enfermedad que se genera en la glándula mamaria y se da dentro de los corrales de encierre, por el contacto de la ubre con el suelo.

“Nosotros generamos un cubículo que se adapta a tres configuraciones. Lo que hace es elevar al animal de la zona en la que se encuentra. Es decir, le hacemos una plataforma, un suelo. Ofrece la ventaja de ser transportable, higienizable y tiene un sistema de drenaje por medio de ranuras, eso tiene una caída a un contendor. Ese contenedor le da versatilidad al productor, de acuerdo a la cantidad de animales que tiene poder”.

Contó que su principal competencia es el hormigón y que su objetivo es reducir la mastitis para que el animal llegue lo más limpio posible al sector de ordeñe.

 

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    Oligomeric 3-APs, cyclostellettamines A-F (53-fifty eight), are identified to act as
    antagonists of muscarinic acetylcholine receptors. The IC so binding values vary from 26- to 474 ~g/mL, and their efficiency decreases with the size
    of the alkyl chains linking the pyridinium rings . EGF-lively components , which
    might be structurally much like poly-APS, forestall binding of epidermal
    development components to their receptors on cell
    membranes, leading to decreased DNA synthesis and cell proliferation.
    These compounds additionally bind to insulin receptors, albeit with about
    10 fold lesser affinity . A decrease of radioactivity in the intracellular amino acid pool signifies the significant inhibition of aminoacid transport into cells.
    More detailed research on peculiarities of glycoside-sterol interplay had been carried out using bilayer membranes .

    Studies In Natural Product Chemistry, Volume 27: Bioactive Natural Products, Half H (Research In Pure Products Chemistry)

    Of these, Hst1p is essentially the most intently related to Sir2p
    and in addition localizes predominantly within the nucleus.

    Furthermore, SAHA inhibited the incidence and growth of carcinogen-induced mammary
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    transgenic mannequin mouse of therapyresistant acute promyelocytic leukemia .

    Pyroxamide was shown to induce progress inhibition of tumor cells .

    Pyroxamide (suberoyl-three-aminopyridineamide hydroxamic acid) is a brand new member of
    the hydroxamic acid-primarily based hybrid polar compounds and was designed
    to increase solubility in aqueous solution in contrast with SAHA.

    LAQ-824 is a novel cinnamyl hydroxamic acid
    spinoff (Fig. 1B).

    The part I trial of SAHA has been accomplished, and the outcomes showed that it might be administered safely and had
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    Holothurin A 2 triggered a pointy increase in ion conductivity
    in bilayer membranes containing sterols [ ]. BLM conductivity
    depends on glycoside concentration on this case, displaying the potential of ion pore formation in membranes.

    At low concentrations of holothurin A2 (zero.1 ng/ml) on each side of the
    lipid-cholesterol bilayer, the discrete sudden change of conductivity is expounded to the
    formation of solitary channels. The conductivity of those channels had a definite most at 28±4
    pSm and a imply life time of 12 milliseconds. Bilateral mode of holothurin A 2 impact on BLM shows that newly generated channels consist
    of two semipores. Conductivity levels ranged from 4 to 8 pSm at holothurin A 2 focus from 10 to a hundred ng/ml.
    The formation of «huge» channels apparently results from structural cooperative transitions in bilayers due to the fusion of
    solitary channels or the inclusion of latest subunit complexes into holothurin channels.

    Loya et al. investigated the exercise towards HIV-l RT
    in the organic extract of the purple sea sponge Toxic/ona toxius.
    Five novel natural compounds, particularly toxiusol,
    Fig. , shaagrockol Band C, toxicol A, all of which are sulphated hexaprenoid hydroquinones, and toxicol E, the phydroquinone by-product of
    toxicol A, have been isolated.
    Recently, it has been shown that the C-terminus
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    The capacity to modulate histone acetylation in a gene-particular trend
    presents a challenge for cells. The state of histone acetylation is determined by
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    Fine regulation of the catalytic actions of those enzymes likely entails cooperative subunit interaction and posttranslational modification. However, our limited understanding of the regulation of gene-specific histone acetylation is finest captured in the quite simplistic model of native
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    ) Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins resulting in specific
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    In human colorectal most cancers cells, a mix of apicidin and proteasome inhibitors MG132,
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    Extracts prepared from economically necessary marine bivalves were found to possess high antiviral activity when examined
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    Literally thousands of plant species have been tested towards
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    Mammalian polycomb-group homologues are regarded as unfavorable regulators of homeotic
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    of theDrosophila additional intercourse combs Pc-G protein. In parallel with the developments in our understanding
    of HDACs, there have additionally been the recent identification and useful
    evaluation of several human histone acetyltransferases and the mechanisms by which
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    By Construction

    AChE exercise of poly-APS has been studied in detail .
    However, the kinetics of AChE inhibition by poly-APS
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    inhibition of the enzyme. The irreversible part
    is probably accounted for by aggregation and precipitation of
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    studied in detail . Poly-APS weren’t able to
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    3-AP compounds also can bind and modulate the exercise of certain receptors.

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    An increase in glycoside dose from 0.1 to 1.0 ng/ml caused the
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    channels, having»small» sizes, to that of bigger
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    . activity in opposition to the influenza A virus for Microcystis aeruginosa, Microcystis ichthyoblabe and Microcystis
    wesenbergii. The antiviral exercise noticed was associated with protease inhibitory activity
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    virus replication. Nowotny et al. investigated in more element the
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    Another anti-influenza compound from marine origin included a brand new sesquiterpene hydroquinone, named strongylin A, which was isolated from the marine sponge Strongylophora hartmani .
    Sorbicillactone A is another alkaloid isolated from a pressure
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    The compound displays promising activities in several viral test systems, in particular the flexibility to guard human T cells in opposition to the ePE of HIV-1.

    All compounds exhibited inhibitory activity of
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    H exercise. Prenylhydroquinone sulphates, which inhibit HIV-integrase enzymes, have been isolated from the marine sponge Ircinia spp.

    Excitement within the subject of chromatin structure has been generated with the belief that remodeling mechanisms may be targeted in therapeutic methods.

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    Holothurin A 2 impacts the functioning lipid-ergosterol
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    The antiviral effect was verified in the Allantois on shell techniques using different subtypes of influenza virus A and B .
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    of influenza virus type A and B in vitro and in ovo . The inhibition affected adsorption in addition to
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